High‐definition simulation of packed‐bed liquid chromatography

Molecular simulation studies of reversed-phase liquid chromatography.

Over the past 20 years, molecular simulation methods have been applied to the modeling of reversed-phase liquid chromatography (RPLC). The purpose of these simulations was to provide a molecular-level understanding of: (i) the structure and dynamics of the bonded phase and its interface with the mobile phase, (ii) the interactions of analytes with the bonded phase, and (iii) the retention mecha...

Ion Exclusion Chromatography: Liquid Chromatography

terials, operated in a pressure-driven mode, plotted as a function of inverse temperature. This Rgure is intended to give some appreciation of the Suxes that are attainable; however, they are not normalized to a given partial pressure gradient or thickness of membrane, and thus the Suxes are not directly comparable. Taking a value of between 10 and 100 L m 2 min 1 as the level of oxygen Sux nee...

Liquid chromatography.

Liquid Chromatography

Polarity Reversed-phase chromatography and hydrophobic-interaction chromatography Centrifugation: Analytical Centrifugation. Chromatography: Protein Separation. III/Enzymes: Liquid Chromatography. Proteins: Capillary Electrophoresis; Centrifugation; Crystallization; Electrophoresis; Glycoproteins: Liquid Chromatography; High-Speed Countercurrent Chromatography; Ion Exchange; Metalloproteins: Ch...

Separation of Sedative – Hypnotic Drugs with Mixed Micellar Liquid Chromatography

Separation of ten sedative- hypnotic drugs was performed by RP-HPLC using mixed micellar mobile phase. Effect of temperature, type and amount of organic modifier in mobile phase on efficiency (N) and asymmetry factor (B/A) showed that, the appropriate conditions for a good separation were 35°C and 7% (V/V) butanol in mobile phase.  Variations of selectivity factor versus butanol concent...